Junction plakoglobin regulates and destabilizes HIF2α to inhibit tumorigenesis of renal cell carcinoma

BACKGROUND: Increased hypoxia‐inducible factor 2α (HIF2α) activation is a common event in clear cell renal cell carcinoma (ccRCC) progression. However, the function and underlying mechanism of HIF2α in ccRCC remains uninvestigated. We conducted this study to access the potential link between junctio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Commun (Lond)
Prif Awduron: Chen, Ke, Zeng, Jin, Sun, Yi, Ouyang, Wei, Yu, Gan, Zhou, Hui, Zhang, Yangjun, Yao, Weimin, Xiao, Wei, Hu, Junhui, Xing, Jinchun, Xiao, Kefeng, Wu, Lily, Chen, Zhiqiang, Ye, Zhangqun, Xu, Hua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2021
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045910/
https://ncbi.nlm.nih.gov/pubmed/33591636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cac2.12142
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