Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma

SMYD2 is a histone methyltransferase that has been reported to be an important epigenetic regulator. This study aims to investigate SMYD2 as a prognostic indicator of clear cell renal cell carcinoma (ccRCC) and explore its role in tumorigenesis and multi-drug resistance. Methods: Tumor specimens, cl...

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Bibliografiske detaljer
Udgivet i:Theranostics
Main Authors: Yan, Libin, Ding, Beichen, Liu, Haoran, Zhang, Yangjun, Zeng, Jin, Hu, Junhui, Yao, Weimin, Yu, Gan, An, Ruihua, Chen, Zhiqiang, Ye, Zhangqun, Xing, Jinchun, Xiao, Kefeng, Wu, Lily, Xu, Hua
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857066/
https://ncbi.nlm.nih.gov/pubmed/31754403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37628
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