HIF-1α promoted vasculogenic mimicry formation in lung adenocarcinoma through NRP1 upregulation in the hypoxic tumor microenvironment

Neovascularization is a key factor that contributes to tumor metastasis, and vasculogenic mimicry (VM) is an important form of neovascularization found in highly invasive tumors, including lung cancer. Despite the increasing number of studies focusing on VM, the mechanisms underlying VM formation re...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Fu, Ran, Du, Wenwen, Ding, Zongli, Wang, Yi, Li, Yue, Zhu, Jianjie, Zeng, Yuanyuan, Zheng, Yulong, Liu, Zeyi, Huang, Jian-an
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044151/
https://ncbi.nlm.nih.gov/pubmed/33850110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03682-z
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