A Chinese Herbal Formula Suppresses Colorectal Cancer Migration and Vasculogenic Mimicry Through ROS/HIF-1α/MMP2 Pathway in Hypoxic Microenvironment

Various malignant tumors, including colorectal cancer, have the ability to form functional blood vessels for tumor growth and metastasis. Vasculogenic mimicry (VM) refers to the ability of highly invasive tumor cells to link each other to form vessels, which is associated with poor cancer prognosis....

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Zong, Shaoqi, Tang, Yufei, Li, Wen, Han, Susu, Shi, Qi, Ruan, Xiaofeng, Hou, Fenggang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242742/
https://ncbi.nlm.nih.gov/pubmed/32499699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00705
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