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A trimeric hydrophobic zipper mediates the intramembrane assembly of SARS-CoV-2 spike
The S protein of the SARS-CoV-2 is a Type I membrane protein that mediates membrane fusion and viral entry. A vast amount of structural information is available for the ectodomain of S, a primary target by the host immune system, but much less is known regarding its transmembrane domain (TMD) and it...
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| Pubblicato in: | bioRxiv |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8043453/ https://ncbi.nlm.nih.gov/pubmed/33851163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.04.09.439203 |
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