A thermostable, closed SARS-CoV-2 spike protein trimer.

The spike (S) protein of SARS-CoV-2 mediates receptor binding and cell entry and is the dominant target of the immune system. S exhibits substantial conformational flexibility. It transitions from closed to open conformations to expose its receptor-binding site, and subsequently from prefusion to po...

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Bibliografski detalji
Izdano u:Nat Struct Mol Biol
Glavni autori: Xiong, Xiaoli, Qu, Kun, Ciazynska, Katarzyna A., Hosmillo, Myra, Carter, Andrew P., Ebrahimi, Soraya, Ke, Zunlong, Scheres, Sjors H.W., Bergamaschi, Laura, Grice, Guinevere L., Zhang, Ying, Nathan, James A., Baker, Stephen, James, Leo C., Baxendale, Helen E., Goodfellow, Ian, Doffinger, Rainer, Briggs, John A.G.
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116388/
https://ncbi.nlm.nih.gov/pubmed/32737467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0478-5
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