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A trimeric hydrophobic zipper mediates the intramembrane assembly of SARS-CoV-2 spike

The S protein of the SARS-CoV-2 is a Type I membrane protein that mediates membrane fusion and viral entry. A vast amount of structural information is available for the ectodomain of S, a primary target by the host immune system, but much less is known regarding its transmembrane domain (TMD) and it...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Fu, Qingshan, Chou, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043453/
https://ncbi.nlm.nih.gov/pubmed/33851163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.04.09.439203
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