A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding

PDZ domains are one of the most abundant protein domains in eukaryotes and are frequently found on junction-localized scaffold proteins. Various signaling molecules bind to PDZ proteins via PDZ-binding motifs (PBM) and fine-tune cellular signaling. However, how such interaction affects protein funct...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Ear, Jason, Abd El-Hafeez, Amer Ali, Roy, Suchismita, Ngo, Tony, Rajapakse, Navin, Choi, Julie, Khandelwal, Soni, Ghassemian, Majid, McCaffrey, Luke, Kufareva, Irina, Sahoo, Debashis, Ghosh, Pradipta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042451/
https://ncbi.nlm.nih.gov/pubmed/33675748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100493
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