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A Cas9–transcription factor fusion protein enhances homology-directed repair efficiency
Precise gene insertion or replacement in cells and animals that requires incorporation of a foreign DNA template into the genome target site by homology-directed repair (HDR) remains an inefficient process. One of the limiting factors for the inefficiency of HDR lies in the limited chance for coloca...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8042446/ https://ncbi.nlm.nih.gov/pubmed/33689695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100525 |
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