Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in Drosophila

We and others recently demonstrated that the readily programmable CRISPR/Cas9 system can be used to edit the Drosophila genome. However, most applications to date have relied on aberrant DNA repair to stochastically generate frameshifting indels and adoption has been limited by a lack of tools for e...

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Detaylı Bibliyografya
Asıl Yazarlar: Gratz, Scott J., Ukken, Fiona P., Rubinstein, C. Dustin, Thiede, Gene, Donohue, Laura K., Cummings, Alexander M., O’Connor-Giles, Kate M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2014
Konular:
Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982687/
https://ncbi.nlm.nih.gov/pubmed/24478335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.160713
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