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Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in Drosophila

We and others recently demonstrated that the readily programmable CRISPR/Cas9 system can be used to edit the Drosophila genome. However, most applications to date have relied on aberrant DNA repair to stochastically generate frameshifting indels and adoption has been limited by a lack of tools for e...

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Détails bibliographiques
Auteurs principaux: Gratz, Scott J., Ukken, Fiona P., Rubinstein, C. Dustin, Thiede, Gene, Donohue, Laura K., Cummings, Alexander M., O’Connor-Giles, Kate M.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982687/
https://ncbi.nlm.nih.gov/pubmed/24478335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.160713
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