Methods for Enhancing Clustered Regularly Interspaced Short Palindromic Repeats/Cas9-Mediated Homology-Directed Repair Efficiency

The evolution of organisms has provided a variety of mechanisms to maintain the integrity of its genome, but as damage occurs, DNA damage repair pathways are necessary to resolve errors. Among them, the DNA double-strand break repair pathway is highly conserved in eukaryotes, including mammals. Nonh...

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Vydáno v:Front Genet
Hlavní autoři: Tang, Xi-Dian, Gao, Fei, Liu, Ming-Jie, Fan, Qin-Lei, Chen, De-Kun, Ma, Wen-Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590329/
https://ncbi.nlm.nih.gov/pubmed/31263478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00551
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