Airway Epithelial Inflammation In Vitro Augments the Rescue of Mutant CFTR by Current CFTR Modulator Therapies

In cystic fibrosis (CF), defective biogenesis and activity of the cystic fibrosis transmembrane conductance regulator (CFTR) leads to airway dehydration and impaired mucociliary clearance, resulting in chronic airway infection and inflammation. The most common CFTR mutation, F508del, results in a pr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Gentzsch, Martina, Cholon, Deborah M., Quinney, Nancy L., Martino, Mary E. B., Minges, John T., Boyles, Susan E., Guhr Lee, Tara N., Esther, Charles R., Ribeiro, Carla M. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042279/
https://ncbi.nlm.nih.gov/pubmed/33859562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.628722
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados