Substrates Modulate Charge-Reorganization Allosteric Effects in Protein–Protein Association

[Image: see text] Protein function may be modulated by an event occurring far away from the functional site, a phenomenon termed allostery. While classically allostery involves conformational changes, we recently observed that charge redistribution within an antibody can also lead to an allosteric e...

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Publicat a:J Phys Chem Lett
Autors principals: Ghosh, Shirsendu, Banerjee-Ghosh, Koyel, Levy, Dorit, Riven, Inbal, Naaman, Ron, Haran, Gilad
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2021
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041378/
https://ncbi.nlm.nih.gov/pubmed/33710900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.1c00437
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