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Signal transduction through Cys-loop receptors is mediated by the nonspecific bumping of closely apposed domains
One of the most fundamental questions in the field of Cys-loop receptors (pentameric ligand-gated ion channels, pLGICs) is how the affinity for neurotransmitters and the conductive/nonconductive state of the transmembrane pore are correlated despite the ∼60-Å distance between the corresponding domai...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8040799/ https://ncbi.nlm.nih.gov/pubmed/33785596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021016118 |
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