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A Crucial Role for Side-Chain Conformation in the Versatile Charge Selectivity of Cys-Loop Receptors

Whether synaptic transmission is excitatory or inhibitory depends, to a large extent, on whether the ion channels that open upon binding the released neurotransmitter conduct cations or anions. The mechanistic basis of the opposite charge selectivities of Cys-loop receptors has only recently begun t...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Harpole, Tyler J., Grosman, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506641/
https://ncbi.nlm.nih.gov/pubmed/31005237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.03.022
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