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Principles of activation and permeation in an anion-selective Cys-loop receptor

Fast inhibitory neurotransmission is essential for nervous system function and is mediated by binding of inhibitory neurotransmitters to receptors of the Cys-loop family embedded in the membranes of neurons. Neurotransmitter binding triggers a conformational change in the receptor, opening an intrin...

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Détails bibliographiques
Auteurs principaux: Hibbs, Ryan E., Gouaux, Eric
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160419/
https://ncbi.nlm.nih.gov/pubmed/21572436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10139
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