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X-ray structures of GluCl in apo states reveal gating mechanism of Cys-loop receptors

Cys-loop receptors are neurotransmitter-gated ion channels that are essential mediators of fast chemical neurotransmission and are associated with a large number of neurological diseases and disorders, as well as parasitic infections(1–4). Members of this ion channel superfamily mediate excitatory o...

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Pubblicato in:Nature
Autori principali: Althoff, Thorsten, Hibbs, Ryan E., Banerjee, Surajit, Gouaux, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255919/
https://ncbi.nlm.nih.gov/pubmed/25143115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13669
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