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Functional Evaluation of Key Interactions Evident in the Structure of the Eukaryotic Cys-Loop Receptor GluCl

[Image: see text] The publication of the first high-resolution crystal structure of a eukaryotic Cys-loop receptor, GluClα, has provided valuable structural information on this important class of ligand-gated ion channels (LGIC). However, limited functional data exist for the GluCl receptors. Before...

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Detalhes bibliográficos
Main Authors: Daeffler, Kristina N.-M., Lester, Henry A., Dougherty, Dennis A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201344/
https://ncbi.nlm.nih.gov/pubmed/25051140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500323d
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