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Functionally Important Aromatic-Aromatic and Sulfur-π Interactions in the D2 Dopamine Receptor

The recently published crystal structure of the D3 dopamine receptor shows a tightly packed region of aromatic residues on helices 5 and 6 in the space bridging the binding site and what is thought to be the origin of intracellular helical motion. This highly conserved region also makes contacts wit...

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Detalhes bibliográficos
Main Authors: Daeffler, Kristina N.-M., Lester, Henry A., Dougherty, Dennis A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461201/
https://ncbi.nlm.nih.gov/pubmed/22897614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja304560x
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