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GluCl a target of indole alkaloid okaramines: a 25 year enigma solved

In 1989, indole alkaloid okaramines isolated from the fermentation products of Penicillium simplicissimum were shown to be insecticidal, yet the mechanism of their toxicity to insects remains unknown. We therefore examined the action of okaramine B on silkworm larval neurons using patch-clamp electr...

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Bibliografiske detaljer
Main Authors: Furutani, Shogo, Nakatani, Yuri, Miura, Yuka, Ihara, Makoto, Kai, Kenji, Hayashi, Hideo, Matsuda, Kazuhiko
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143795/
https://ncbi.nlm.nih.gov/pubmed/25155752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06190
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