Loss of hepatic Mboat7 leads to liver fibrosis

OBJECTIVE: The rs641738C>T variant located near the membrane-bound O-acyltransferase domain containing 7 (MBOAT7) locus is associated with fibrosis in liver diseases, including non-alcoholic fatty liver disease (NAFLD), alcohol-related liver disease, hepatitis B and C. We aim to understand the me...

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Опубликовано в: :Gut
Главные авторы: Thangapandi, Veera Raghavan, Knittelfelder, Oskar, Brosch, Mario, Patsenker, Eleonora, Vvedenskaya, Olga, Buch, Stephan, Hinz, Sebastian, Hendricks, Alexander, Nati, Marina, Herrmann, Alexander, Rekhade, Devavrat Ravindra, Berg, Thomas, Matz-Soja, Madlen, Huse, Klaus, Klipp, Edda, Pauling, Josch K, Wodke, Judith AH, Miranda Ackerman, Jacobo, von Bonin, Malte, Aigner, Elmar, Datz, Christian, von Schönfels, Witigo, Nehring, Sophie, Zeissig, Sebastian, Röcken, Christoph, Dahl, Andreas, Chavakis, Triantafyllos, Stickel, Felix, Shevchenko, Andrej, Schafmayer, Clemens, Hampe, Jochen, Subramanian, Pallavi
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2021
Предметы:
Hepatology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040158/
https://ncbi.nlm.nih.gov/pubmed/32591434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2020-320853
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