Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control

A deeper epigenomic understanding of spatial organization of cells in human tissues is an important challenge. Here we report the first combined positional analysis of transcriptomes and methylomes across three micro-dissected zones (pericentral, intermediate and periportal) of human liver. We ident...

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Publicado no:Nat Commun
Main Authors: Brosch, Mario, Kattler, Kathrin, Herrmann, Alexander, von Schönfels, Witigo, Nordström, Karl, Seehofer, Daniel, Damm, Georg, Becker, Thomas, Zeissig, Sebastian, Nehring, Sophie, Reichel, Fabian, Moser, Vincent, Thangapandi, Raghavan Veera, Stickel, Felix, Baretton, Gustavo, Röcken, Christoph, Muders, Michael, Matz-Soja, Madlen, Krawczak, Michael, Gasparoni, Gilles, Hartmann, Hella, Dahl, Andreas, Schafmayer, Clemens, Walter, Jörn, Hampe, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175862/
https://ncbi.nlm.nih.gov/pubmed/30297808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06611-5
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