Loss of hepatic Mboat7 leads to liver fibrosis

OBJECTIVE: The rs641738C>T variant located near the membrane-bound O-acyltransferase domain containing 7 (MBOAT7) locus is associated with fibrosis in liver diseases, including non-alcoholic fatty liver disease (NAFLD), alcohol-related liver disease, hepatitis B and C. We aim to understand the me...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Thangapandi, Veera Raghavan, Knittelfelder, Oskar, Brosch, Mario, Patsenker, Eleonora, Vvedenskaya, Olga, Buch, Stephan, Hinz, Sebastian, Hendricks, Alexander, Nati, Marina, Herrmann, Alexander, Rekhade, Devavrat Ravindra, Berg, Thomas, Matz-Soja, Madlen, Huse, Klaus, Klipp, Edda, Pauling, Josch K, Wodke, Judith AH, Miranda Ackerman, Jacobo, von Bonin, Malte, Aigner, Elmar, Datz, Christian, von Schönfels, Witigo, Nehring, Sophie, Zeissig, Sebastian, Röcken, Christoph, Dahl, Andreas, Chavakis, Triantafyllos, Stickel, Felix, Shevchenko, Andrej, Schafmayer, Clemens, Hampe, Jochen, Subramanian, Pallavi
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040158/
https://ncbi.nlm.nih.gov/pubmed/32591434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2020-320853
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