Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria

Reactive oxygen species (ROS) are a common product of active mitochondrial respiration carried in mitochondrial cristae, but whether cristae shape influences ROS levels is unclear. Here we report that the mitochondrial fusion and cristae shape protein Opa1 requires mitochondrial ATP synthase oligome...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Quintana-Cabrera, Rubén, Manjarrés-Raza, Israel, Vicente-Gutiérrez, Carlos, Corrado, Mauro, Bolaños, Juan P., Scorrano, Luca
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039725/
https://ncbi.nlm.nih.gov/pubmed/33780775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101944
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