Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria

Reactive oxygen species (ROS) are a common product of active mitochondrial respiration carried in mitochondrial cristae, but whether cristae shape influences ROS levels is unclear. Here we report that the mitochondrial fusion and cristae shape protein Opa1 requires mitochondrial ATP synthase oligome...

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Sparad:
Bibliografiska uppgifter
I publikationen:Redox Biol
Huvudupphovsmän: Quintana-Cabrera, Rubén, Manjarrés-Raza, Israel, Vicente-Gutiérrez, Carlos, Corrado, Mauro, Bolaños, Juan P., Scorrano, Luca
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2021
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039725/
https://ncbi.nlm.nih.gov/pubmed/33780775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101944
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