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Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria

Aging is one of the most fundamental, yet least understood biological processes that affect all forms of eukaryotic life. Mitochondria are intimately involved in aging, but the underlying molecular mechanisms are largely unknown. Electron cryotomography of whole mitochondria from the aging model org...

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Detalhes bibliográficos
Main Authors: Daum, Bertram, Walter, Andreas, Horst, Angelika, Osiewacz, Heinz D., Kühlbrandt, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780843/
https://ncbi.nlm.nih.gov/pubmed/24006361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305462110
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