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Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening

Despite extensive and intensive research efforts in recent decades, there is still no effective treatment for neurodegenerative diseases. On this background, the use of drugs inhibiting the enzyme acetylcholinesterase (AChE) remains an eternal evergreen in the symptomatic treatment of mild to modera...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Stavrakov, Georgi, Philipova, Irena, Lukarski, Atanas, Atanasova, Mariyana, Georgiev, Borislav, Atanasova, Teodora, Konstantinov, Spiro, Doytchinova, Irini
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038331/
https://ncbi.nlm.nih.gov/pubmed/33916760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26072058
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