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Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors

The past decade revealed that cell identity changes, such as dedifferentiation or transdifferentiation, accompany the insulin-producing β-cell decay in most diabetes conditions. Mapping and controlling the mechanisms governing these processes is, thus, extremely valuable for managing the disease pro...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ghila, Luiza, Legøy, Thomas Aga, Mathisen, Andreas Frøslev, Abadpour, Shadab, Paulo, Joao A., Scholz, Hanne, Ræder, Helge, Chera, Simona
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038174/
https://ncbi.nlm.nih.gov/pubmed/33918250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073698
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