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CRISPR Screens in Synthetic Lethality and Combinatorial Therapies for Cancer
SIMPLE SUMMARY: The synthetic lethality (SL) clinical success of PARP inhibitors in homologous recombinant deficient tumors has established a new concept for cancer treatment. For decades, efforts have centered on identifying genetic interactions for determining essential tumoral genes, and more rec...
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| 出版年: | Cancers (Basel) |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8037779/ https://ncbi.nlm.nih.gov/pubmed/33808217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071591 |
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