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Synthetic Lethality Screens Using RNAi in Combination with CRISPR-based Knockout in Drosophila Cells

A synthetic lethal interaction is a type of genetic interaction where the disruption of either of two genes individually has little effect but their combined disruption is lethal. Knowledge of synthetic lethal interactions can allow for elucidation of network structure and identification of candidat...

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Bibliografische gegevens
Gepubliceerd in:Bio Protoc
Hoofdauteurs: Housden, Benjamin E., Nicholson, Hilary E., Perrimon, Norbert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Bio-Protocol 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432019/
https://ncbi.nlm.nih.gov/pubmed/28523286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2119
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