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Synthetic Lethality Screens Using RNAi in Combination with CRISPR-based Knockout in Drosophila Cells
A synthetic lethal interaction is a type of genetic interaction where the disruption of either of two genes individually has little effect but their combined disruption is lethal. Knowledge of synthetic lethal interactions can allow for elucidation of network structure and identification of candidat...
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| Published in: | Bio Protoc |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Bio-Protocol
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5432019/ https://ncbi.nlm.nih.gov/pubmed/28523286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2119 |
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