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Synthetic Lethality Screens Using RNAi in Combination with CRISPR-based Knockout in Drosophila Cells

A synthetic lethal interaction is a type of genetic interaction where the disruption of either of two genes individually has little effect but their combined disruption is lethal. Knowledge of synthetic lethal interactions can allow for elucidation of network structure and identification of candidat...

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Detalles Bibliográficos
Publicado en:Bio Protoc
Autores principales: Housden, Benjamin E., Nicholson, Hilary E., Perrimon, Norbert
Formato: Artigo
Lenguaje:Inglês
Publicado: Bio-Protocol 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432019/
https://ncbi.nlm.nih.gov/pubmed/28523286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2119
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