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Synthetic Lethality Screens Using RNAi in Combination with CRISPR-based Knockout in Drosophila Cells

A synthetic lethal interaction is a type of genetic interaction where the disruption of either of two genes individually has little effect but their combined disruption is lethal. Knowledge of synthetic lethal interactions can allow for elucidation of network structure and identification of candidat...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Housden, Benjamin E., Nicholson, Hilary E., Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432019/
https://ncbi.nlm.nih.gov/pubmed/28523286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2119
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