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Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors
A new type of berberine derivatives was obtained by the reaction of berberrubine with aliphatic sulfonyl chlorides. The new polycyclic compounds have a sultone ring condensed to C and D rings of a protoberberine core. The reaction conditions were developed to facilitate the formation of sultones wit...
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| Udgivet i: | Molecules |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8037669/ https://ncbi.nlm.nih.gov/pubmed/33808389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26071945 |
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