A carregar...

Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors

A new type of berberine derivatives was obtained by the reaction of berberrubine with aliphatic sulfonyl chlorides. The new polycyclic compounds have a sultone ring condensed to C and D rings of a protoberberine core. The reaction conditions were developed to facilitate the formation of sultones wit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Gladkova, Elizaveta D., Chepanova, Arina A., Ilina, Ekaterina S., Zakharenko, Alexandra L., Reynisson, Jóhannes, Luzina, Olga A., Volcho, Konstantin P., Lavrik, Olga I., Salakhutdinov, Nariman F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037669/
https://ncbi.nlm.nih.gov/pubmed/33808389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26071945
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!