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Adaptability and Specificity: How do proteins balance opposing needs to achieve function?

Many proteins select from a small repertoire of 3-dimensional folds retained over evolutional timescales and recruited for different functions, with changes in local structure and sequence to enable specificity. Recent studies have revealed the evolutionary constraints on protein dynamics to achieve...

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Dades bibliogràfiques
Publicat a:Curr Opin Struct Biol
Autors principals: Wingert, Bentley, Krieger, James, Li, Hongchun, Bahar, Ivet
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036234/
https://ncbi.nlm.nih.gov/pubmed/33053463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.08.009
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