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Pharmmaker: Pharmacophore modeling and hit identification based on druggability simulations

Recent years have seen progress in druggability simulations, that is, molecular dynamics simulations of target proteins in solutions containing drug‐like probe molecules to characterize their drug‐binding abilities, if any. An important consecutive step is to analyze the trajectories to construct ph...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Lee, Ji Young, Krieger, James M., Li, Hongchun, Bahar, Ivet
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933858/
https://ncbi.nlm.nih.gov/pubmed/31576621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3732
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