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Shared Signature Dynamics Tempered by Local Fluctuations Enables Fold Adaptability and Specificity

Recent studies have drawn attention to the evolution of protein dynamics, in addition to sequence and structure, based on the premise structure-encodes-dynamics-encodes-function. Of interest is to understand how functional differentiation is accomplished while maintaining the fold, or how intrinsic...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Zhang, She, Li, Hongchun, Krieger, James M, Bahar, Ivet
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736388/
https://ncbi.nlm.nih.gov/pubmed/31028708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz102
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