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Shared dynamics of LeuT superfamily members and allosteric differentiation by structural irregularities and multimerization

The LeuT-fold superfamily includes secondary active transporters from different functional families, which share a common tertiary structure, despite having a remarkably low sequence similarity. By identifying the common structural and dynamical features upon principal component analysis of a compre...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Main Authors: Ponzoni, Luca, Zhang, She, Cheng, Mary Hongying, Bahar, Ivet
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941172/
https://ncbi.nlm.nih.gov/pubmed/29735731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0177
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