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Microseconds Simulations Reveal a New Sodium-binding Site and the Mechanism of Sodium-coupled Substrate Uptake by LeuT

The bacterial sodium-coupled leucine/alanine transporter LeuT is broadly used as a model system for studying the transport mechanism of neurotransmitters because of its structural and functional homology to mammalian transporters such as serotonin, dopamine, or norepinephrine transporters, and becau...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zomot, Elia, Gur, Mert, Bahar, Ivet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281755/
https://ncbi.nlm.nih.gov/pubmed/25381247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.617555
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