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Substrate and drug binding sites in LeuT

LeuT is a member of the neurotransmitter/sodium symporter family, which includes the neuronal transporters for serotonin, norepinephrine and dopamine. The original crystal structure of LeuT shows a primary leucine binding site at the center of the protein. LeuT is inhibited by different classes of a...

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Detalhes bibliográficos
Main Authors: Nyola, Ajeeta, Karpowich, Nathan K., Zhen, Juan, Marden, Jennifer, Reith, Maarten E., Wang, Da-Neng
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925194/
https://ncbi.nlm.nih.gov/pubmed/20739005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2010.05.007
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