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Resculpting the binding pocket of APC superfamily LeuT-fold amino acid transporters

Amino acid transporters are essential components of prokaryote and eukaryote cells, possess distinct physiological functions, and differ markedly in substrate specificity. Amino acid transporters can be both drug targets and drug transporters (bioavailability, targeting) with many monogenic disorder...

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Bibliografske podrobnosti
izdano v:Cell Mol Life Sci
Main Authors: Edwards, Noel, Anderson, Catriona M. H., Conlon, Nichola J., Watson, Andrew K., Hall, Rebecca J., Cheek, Timothy R., Embley, T. Martin, Thwaites, David T.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809530/
https://ncbi.nlm.nih.gov/pubmed/29058016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2677-8
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