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Resculpting the binding pocket of APC superfamily LeuT-fold amino acid transporters
Amino acid transporters are essential components of prokaryote and eukaryote cells, possess distinct physiological functions, and differ markedly in substrate specificity. Amino acid transporters can be both drug targets and drug transporters (bioavailability, targeting) with many monogenic disorder...
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| 出版年: | Cell Mol Life Sci |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer International Publishing
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5809530/ https://ncbi.nlm.nih.gov/pubmed/29058016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2677-8 |
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