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Intrinsic dynamics is evolutionarily optimized to enable allosteric behavior

Allosteric behavior is central to the function of many proteins, enabling molecular machinery, metabolism, signaling and regulation. Recent years have shown that the intrinsic dynamics of allosteric proteins defined by their 3-dimensional architecture or by the topology of inter-residue contacts fav...

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Bibliografiske detaljer
Udgivet i:Curr Opin Struct Biol
Main Authors: Zhang, Yan, Doruker, Pemra, Kaynak, Burak, Zhang, She, Krieger, James, Li, Hongchun, Bahar, Ivet
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250723/
https://ncbi.nlm.nih.gov/pubmed/31785465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.11.002
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