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Intrinsic dynamics is evolutionarily optimized to enable allosteric behavior

Allosteric behavior is central to the function of many proteins, enabling molecular machinery, metabolism, signaling and regulation. Recent years have shown that the intrinsic dynamics of allosteric proteins defined by their 3-dimensional architecture or by the topology of inter-residue contacts fav...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Zhang, Yan, Doruker, Pemra, Kaynak, Burak, Zhang, She, Krieger, James, Li, Hongchun, Bahar, Ivet
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250723/
https://ncbi.nlm.nih.gov/pubmed/31785465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.11.002
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