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Development of facile and versatile platinum drug delivering silicasome nanocarriers for efficient pancreatic cancer chemo-immunotherapy

In this study we developed a mesoporous silica nanoparticle (MSNP) based platform for high-dose loading of a range of activated platinum (Pt) chemo agents that could be attached to the porous interior through the use of electrostatic and coordination chemistry under weak-basic pH conditions. In addi...

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Publicado en:Small
Autores principales: Liu, Xiangsheng, Jiang, Jinhong, Chang, Chong Hyun, Liao, Yu-Pei, Lodico, Jared J., Tang, Ivanna, Zheng, Emily, Qiu, Waveley, Lin, Matthew, Wang, Xiang, Ji, Ying, Mei, Kuo-Ching, Nel, Andre E., Meng, Huan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035264/
https://ncbi.nlm.nih.gov/pubmed/33682329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.202005993
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