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Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is almost uniformly fatal; however, some improvement in overall survival has been achieved with the introduction of nanocarriers that deliver irinotecan or paclitaxel. Although it is generally assumed that nanocarriers rely principally on abnormal leaky vascul...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Liu, Xiangsheng, Lin, Paulina, Perrett, Ian, Lin, Joshua, Liao, Yu-Pei, Chang, Chong Hyun, Jiang, Jinhong, Wu, Nanping, Donahue, Timothy, Wainberg, Zev, Nel, Andre E., Meng, Huan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409788/
https://ncbi.nlm.nih.gov/pubmed/28414297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92284
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