Combination Chemo‐Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti‐PD‐1

There is an urgent need to develop new life‐prolonging therapy for pancreatic ductal adenocarcinoma (PDAC). It is demonstrated that improved irinotecan delivery by a lipid bilayer coated mesoporous silica nanoparticle, also known as a silicasome, can improve PDAC survival through a chemo‐immunothera...

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Veröffentlicht in:Adv Sci (Weinh)
Hauptverfasser: Liu, Xiangsheng, Jiang, Jinhong, Liao, Yu‐Pei, Tang, Ivanna, Zheng, Emily, Qiu, Waveley, Lin, Matthew, Wang, Xiang, Ji, Ying, Mei, Kuo‐Ching, Liu, Qi, Chang, Chong Hyun, Wainberg, Zev A., Nel, Andre E., Meng, Huan
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967046/
https://ncbi.nlm.nih.gov/pubmed/33747719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002147
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