Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns

Vertebrate genomes contain major (>99.5%) and minor (<0.5%) introns that are spliced by the major and minor spliceosomes, respectively. Major intron splicing follows the exon-definition model, whereby major spliceosome components first assemble across exons. However, since most genes with mino...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Olthof, Anouk M, White, Alisa K, Mieruszynski, Stephen, Doggett, Karen, Lee, Madisen F, Chakroun, Almahdi, Abdel Aleem, Alice K, Rousseau, Justine, Magnani, Cinzia, Roifman, Chaim M, Campeau, Philippe M, Heath, Joan K, Kanadia, Rahul N
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
Assuntos:
RNA and RNA-protein complexes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034651/
https://ncbi.nlm.nih.gov/pubmed/33660780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab118
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