Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns

Vertebrate genomes contain major (>99.5%) and minor (<0.5%) introns that are spliced by the major and minor spliceosomes, respectively. Major intron splicing follows the exon-definition model, whereby major spliceosome components first assemble across exons. However, since most genes with mino...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Olthof, Anouk M, White, Alisa K, Mieruszynski, Stephen, Doggett, Karen, Lee, Madisen F, Chakroun, Almahdi, Abdel Aleem, Alice K, Rousseau, Justine, Magnani, Cinzia, Roifman, Chaim M, Campeau, Philippe M, Heath, Joan K, Kanadia, Rahul N
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
RNA and RNA-protein complexes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034651/
https://ncbi.nlm.nih.gov/pubmed/33660780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab118
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