Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns

Vertebrate genomes contain major (>99.5%) and minor (<0.5%) introns that are spliced by the major and minor spliceosomes, respectively. Major intron splicing follows the exon-definition model, whereby major spliceosome components first assemble across exons. However, since most genes with mino...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Olthof, Anouk M, White, Alisa K, Mieruszynski, Stephen, Doggett, Karen, Lee, Madisen F, Chakroun, Almahdi, Abdel Aleem, Alice K, Rousseau, Justine, Magnani, Cinzia, Roifman, Chaim M, Campeau, Philippe M, Heath, Joan K, Kanadia, Rahul N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034651/
https://ncbi.nlm.nih.gov/pubmed/33660780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab118
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