Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns

Vertebrate genomes contain major (>99.5%) and minor (<0.5%) introns that are spliced by the major and minor spliceosomes, respectively. Major intron splicing follows the exon-definition model, whereby major spliceosome components first assemble across exons. However, since most genes with mino...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Olthof, Anouk M, White, Alisa K, Mieruszynski, Stephen, Doggett, Karen, Lee, Madisen F, Chakroun, Almahdi, Abdel Aleem, Alice K, Rousseau, Justine, Magnani, Cinzia, Roifman, Chaim M, Campeau, Philippe M, Heath, Joan K, Kanadia, Rahul N
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2021
Pynciau:
RNA and RNA-protein complexes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034651/
https://ncbi.nlm.nih.gov/pubmed/33660780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab118
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