Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns

Vertebrate genomes contain major (>99.5%) and minor (<0.5%) introns that are spliced by the major and minor spliceosomes, respectively. Major intron splicing follows the exon-definition model, whereby major spliceosome components first assemble across exons. However, since most genes with mino...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Olthof, Anouk M, White, Alisa K, Mieruszynski, Stephen, Doggett, Karen, Lee, Madisen F, Chakroun, Almahdi, Abdel Aleem, Alice K, Rousseau, Justine, Magnani, Cinzia, Roifman, Chaim M, Campeau, Philippe M, Heath, Joan K, Kanadia, Rahul N
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
RNA and RNA-protein complexes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034651/
https://ncbi.nlm.nih.gov/pubmed/33660780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab118
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