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Disrupted minor intron splicing is prevalent in Mendelian disorders
BACKGROUND: Splicing is crucial for proper gene expression, and is predominately executed by the major spliceosome. Conversely, 722 introns in 699 human minor intron‐containing genes (MIGs) are spliced by the minor spliceosome. Splicing of these minor introns is disrupted in diseases caused by patho...
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| Опубликовано в: : | Mol Genet Genomic Med |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7507305/ https://ncbi.nlm.nih.gov/pubmed/32573973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1374 |
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