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Disrupted minor intron splicing is prevalent in Mendelian disorders
BACKGROUND: Splicing is crucial for proper gene expression, and is predominately executed by the major spliceosome. Conversely, 722 introns in 699 human minor intron‐containing genes (MIGs) are spliced by the minor spliceosome. Splicing of these minor introns is disrupted in diseases caused by patho...
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| Udgivet i: | Mol Genet Genomic Med |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7507305/ https://ncbi.nlm.nih.gov/pubmed/32573973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1374 |
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