De novo 3D models of SARS-CoV-2 RNA elements from consensus experimental secondary structures

The rapid spread of COVID-19 is motivating development of antivirals targeting conserved SARS-CoV-2 molecular machinery. The SARS-CoV-2 genome includes conserved RNA elements that offer potential small-molecule drug targets, but most of their 3D structures have not been experimentally characterized....

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Rangan, Ramya, Watkins, Andrew M, Chacon, Jose, Kretsch, Rachael, Kladwang, Wipapat, Zheludev, Ivan N, Townley, Jill, Rynge, Mats, Thain, Gregory, Das, Rhiju
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Computational Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034642/
https://ncbi.nlm.nih.gov/pubmed/33693814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab119
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