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RNA genome conservation and secondary structure in SARS-CoV-2 and SARS-related viruses

As the COVID-19 outbreak spreads, there is a growing need for a compilation of conserved RNA genome regions in the SARS-CoV-2 virus along with their structural propensities to guide development of antivirals and diagnostics. Using sequence alignments spanning a range of betacoronaviruses, we rank ge...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Rangan, Ramya, Zheludev, Ivan N., Das, Rhiju
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217285/
https://ncbi.nlm.nih.gov/pubmed/32511306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.03.27.012906
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