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A CRISPR-Cas9–integrase complex generates precise DNA fragments for genome integration
CRISPR-Cas9 is an RNA-guided DNA endonuclease involved in bacterial adaptive immunity and widely repurposed for genome editing in human cells, animals and plants. In bacteria, RNA molecules that guide Cas9′s activity derive from foreign DNA fragments that are captured and integrated into the host CR...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8034620/ https://ncbi.nlm.nih.gov/pubmed/33693715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab123 |
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